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White Dachshunds. Each gene has a unique, fixed location, known as a locus, within the dog genome. Agouti protein controls the release of melanin into the hair and is involved in switching between the two pigments (eumelanin and phaeomelanin). One of these pairs determines the sex of the dog and the rest determine everything else that makes him or her unique. The dog genome contains approximately 3 billion base pairs of DNA and thousands of genes, but only 8 genes in the dog are associated with coat color. In any one gene locus a dog will either be homozygous where the gene is made of two identical alleles (one from its mother and one its father) or heterozygous where the gene is made of two different alleles (one inherited from each parent). Phys.org is a leading web-based science, research and technology news service which covers a full range of topics. [35] The H locus is a modifier locus (of the M locus) and the alleles at the H locus will determine if an animal expresses a harlequin vs merle pattern. Research suggests that hairlessness is caused by a dominant allele of the forkhead box transcription factor (FOXI3) gene, which is homozygous lethal. Before birth, the cells that give color to a kitten's eyes, skin, and hair (called melanocytes) are concentrated . top effect talkative. Genetics of Dog Breeding | Dog Breeding Information It also influences the pheomelanin pigment, which means a sable dog with the harlequin gene can become white with black and tan patches. What happens when you breed a Black GSD to a White GSD? What separates Piebald from Irish White and Solid is the presence of a SINE insertion (Short Interspersed Element) in the S locus genes that changes the normal DNA production. Why white dogs are white - phys.org MITF encodes for a protein (actually a transcription factor - something that controls the use of other genes) that regulates melanocyte migration to different parts of the dog's body during the fetus's development. The wild-type coat in dogs is short, double and straight. 26 White Dog Breeds: Small, Big & Fluffy White Dogs Nicole wants to share her kitty expertise with you so you and your cat. By Two brown genes (bb) gives you a chocolate Labrador. In a classic German Shepherd genetic table - black is a recessive gene and to produce a solid black puppy BOTH . Reduced nose pigment due to piebald. (Phys.org) About half of all dogs show some form of white spotting which can range from a few white marks in the Bernese mountain dog to extreme white coat color in Dalmatians and white boxer.